DY-131 (GSK 9089) 10mg

DY-131 (GSK 9089) – Research Compound
DY-131, also known as GSK 9089, is a synthetic small-molecule agonist that acts selectively on estrogen-related receptors β and γ (ERRβ/γ). It demonstrates high potency and receptor specificity, with no significant activity at ERRα, ERα, or ERβ receptors.

Research interest in DY-131 focuses on its ability to modulate energy metabolism, mitochondrial biogenesis, and cellular signaling pathways governed by ERRβ/γ. Preclinical studies suggest potential applications in oncology, particularly in estrogen receptor-positive breast cancer, as well as in metabolic and mitochondrial dysfunction models. Its receptor selectivity makes it a valuable tool compound for studying ERR-mediated transcriptional activity.